I took an immediate liking to Gruen's subtle intent; very Joseph-Heller-esque (and believe me when I say whoever borrowed-for-good my copy of Catch-22, my heart is broken). Camel may have been my favorite character for this reason - "'It's Camel,' Earl says in a hushed voice. 'He's got trouble. Foot trouble. They've gone all floppy. He kind of slaps them down. His hands aren't so great neither.'" Rosie and Rosemary are a close second, but not second and third. I thought they played too similar an understanding and sustaining role in Jacob's life to differentiate between them both (and not for physical reasons, obviously).
Again, it's fulfilling and will not disappoint. Themes abound, plus, the cover's a good one. I love stripes.